Multiple Choice Questions on Signal Transduction:
1. Regarding signal transduction, which of the following statements is true
A. Only excitable cells can transmit signals
B. Information encoded by action potentials is conducted across synapses
C. External stimuli are conducted on any receptor cell
D. Information enters the cell and causes a cellular response.
Answer: D
2. Which of the following is not an essential characteristic of receptors_______
A. Specificity
B. Affinity
C. Saturation
D. Fidelity
Answer: D
3. Signal transduction steps between cells, the links involving signal molecules are not included
A. is specifically recognized by receptors
B. from extracellular to intracellular
C. Act on second messengers to directly initiate cellular responses
D. Act on intracellular signal transduction molecules to initiate cellular responses
Answer: C
4. Extracellular signaling molecules (ligands) do not include
A. Hormones
B. Cyclins
C. Neurotransmitters
D. Cell adhesion molecules
Answer: B
5. Features of signal transduction generally do not include_____
A. Transient and memory
B. Temporary and reversible
C. Coherence of transduction pathways
D. Specificity and heritability
Answer: D
6. In signal transduction, two types of enzymes that can cause protein conformational changes are______
A. Protein Kinases and Phosphatases
B. Tyrosine Protein Kinases and Tyrosinase
C. Protein Kinase A and Protein Kinase C
D. MAPK and MAPKK
Answer: A
7. The receptor that directly performs the catalytic function of the enzyme after binding to the ligand is________
A. Growth factor receptors
B. Ion channel receptors
C. G protein coupled receptors
D. Nuclear receptors
Answer: A
8. The protein with GTPase activity is______
A. G protein coupled receptor B. G protein
C. Guanylate cyclase
D. Protein Kinase A
Answer: B
9. PKA, PKC, PKG, CaMK, MAPK catalyze which of the following phosphorylation
A. Tyr residues
B. Protein kinase
C. Protein kinase A
D. Ser/Thr residues
Answer: D
10. Cell surface molecules involved in communication do not include
A. Ion channel
B. IP 3
C. Glycoprotein
D. Phosphatidylserine
Answer: B