Molecular Basis of Inheritance NEET Questions

Molecular Basis of Inheritance NEET Questions and Answers Pdf Download :

Molecular Basis of Inheritance is one of the important topic for NEET from which around 5% of the questions appear in the NEET examination every year. So, solving MCQs on Molecular Basis of Inheritance Pdf and following some test series will give an edge in the examination to the NEET aspirants. The number of questions asked from the Molecular Basis of Inheritance in last year was 5. So,  it is advisable to work out as many MCQs as possible through the Molecular Basis of Inheritance online test series. 

Molecular Basis of Inheritance MCQ Questions for NEET preparation is immensely helpful for NEET Exam aspirants. As the NEET Examination is an objective-type paper that also carries negative marking; we have compiled a list of NEET MCQ to give aspirants an idea about the intricacies of the Molecular Basis of Inheritance. There are 50+ questions compiled in the PDF given below. Molecular Basis of Inheritance NEET questions are based on wide-ranging topics of the NEET syllabus. Aspirants can get an idea of what comprises MCQ on Molecular Basis of Inheritance.


Molecular Basis of Inheritance NEET Questions

NEET Questions on Molecular Basis of Inheritance

1. The experimental proof for semiconservative replication of DNA was first shown in a________

(1) Fungus

(2) Bacterium

(3) Plant

(4) Virus

Answer: 2

Read : Morphology of Flowering Plants NEET Questions 

2. Select the correct match__________

(1) Alec Jeffreys – Streptococcus pneumoniae

(2) Alfred Hershey and – TMV Martha Chase

(3) Meselson Stahl – Pisum sativum 

(4) Jacob and Manod –Lac operon

Answer: 4


3. Select the  correct Match_________

(1) Ribozyme - Nucleic acid

(2) F2 × Recessive parent - Dihybrid cross

(3) T.H. Morgan - Transduction

(4) G. Mendel - Transformation

Answer: 1

Read : MCQ on Neural Control and Coordination for NEET 

4. AGGTATCGCAT is a sequence from the coding strand of a gene. What will be the corresponding sequence of the transcribed mRNA ?

(1) AGGUAUCGCAU

(2) UGGTUTCGCAT

(3) ACCUAUGCGAU

(4) UCCAUAGCGUA

Answer: 4


5. Nuclein' term was coined by___________

(1) Meischer and Crick 

(2) Altman

(3) Griffith

(4) Meischer

Answer: 2

Read : DNA replication MCQ 

6. Codons of proline amino acid are_______

(1) CCU CCC CCA

(2) CAU CAC CAA

(3) GGU GGC GGA

(4) AAU AAA AAC

Answer: 1


7. Choose correct one____________

Molecular Basis of Inheritance NEET MCQ

(1) a-DNA, b-H1 -histone, c-histone octamer, d-core of histone

(2) a-core of histone, b-DNA, c-H1 histone, d-histone octamer

(3) a-Histone octamer, b-core of histone, c-DNA, d-H1 histone

(4) a-H1 histone, b-histone octamer, c-core of histone, d-DNA

Answer: 1


8. The mechanism that causes a gene to move from one linkage group to another is called__________

(1) Translocation

(2) Crossing-over

(3) Inversion

(4) Duplication

Answer: 1

Read : MCQ on Mycoplasma 

9. Reverse transcriptase using RNA, forms which of the following ?

(1) Double stranded DNA

(2) Double stranded RNA

(3) DNA & RNA

(4) Single stranded RNA

Answer: 1


10. An immature stop codon leads to_______

(1) Mutation

(2) Non-sense mutation

(3) Variation

(4) Intron

Answer: 2


11. Which of the following is involved in translation_______

(1) DNA

(2) mRNA, tRNA, DNA

(3) mRNA, tRNA

(4) Only mRNA

Answer: 3


12. Which set of RNA are involved in protein synthesis_________

(1) tRNA, mRNA, rRNA

(2) tRNA, mRNA, hnRNA

(3) hnRNA, mRNA, rRNA

(4) hnRNA, tRNA, rRNA

Answer: 1


13. Which of the following is incorrect ?

(1) RNA polymerase II -----> Heterogeneous nuclear RNA

(2) RNA polymerase III -----> t-RNA, Sn-RNA, 5 S-rRNA

(3) RNA polymerase I -----> r-RNA

(4) RNA polymerase I -----> t-RNA, Sn-RNA, 5 S-rRNA

Answer: 4


14. Codon of Arginine amino acid are______

(1) CGU, CGC, CGA

(2) UGU, UGC, UGA

(3) AGU, AGC, AGA

(4) AUA, AUC, AUG

Answer: 1


15. Select the correct statement regarding prokaryotes______

(1) DNA dependent RNA polymerase form all types of RNA.

(2) Different RNA polymerase form different types of RNA.

(3) Single DNA dependent DNA polymerase form one type of RNA.

(4) Different DNA dependent DNA polymerase form one type of RNA.

Answer: 1


16. Which of the following is incorrect for satellite DNA?

(1) High degree of polymorphism.

(2) It is not inherited from parent to children.

(3) It is used in DNA fingerprinting for genetic diversity.

(4) Does not code for any protein.

Answer: 2


17. The process of formation of RNA from DNA is known as_______________

(1) Transcription

(2) Translation

(3) Replication

(4) Transformation

Answer: 1


18. If base sequence in m-RNA is 5' UAC GUA CGU ACG UAC GUA CGU ACG 3' then what will be sequence of template strand?

(1) 5' CGT ACG TAC GTA CGT ACG TAC GTA 3'

(2) 5' TAC GTA CGT ACG TAC GTA CGT ACG 3'

(3) 5' ATG CAT GCA TGC ATG CAT GCA TGC 3'

(4) 5' GTA TAC ACG TGC GTA GTA CAG GCA 3'

Answer: 1


19. DNA fragments are___________

(1) Negatively charged

(2) Neutral

(3) Either positively or negatively charged depending on their size

(4) Positively charged

Answer: 1


20. If there are 999 bases in an RNA that codes for a protein with 333 amino acids, and the base at position 901 is deleted such that the length of the RNA becomes 998 bases, how many codons will be altered ?

(1) 11

(2) 33

(3) 333

(4) 1

Answer: 2


Molecular Basis of Inheritance Questions for NEET

1. During DNA replication, Okazaki fragments are used to elongate__________

(1) The lagging strand towards replication fork.

(2) The leading strand away from replication fork.

(3) The lagging strand away from the replication fork.

(4) The leading strand towards replication fork.

Answer: 3


2. Which of the following RNAs should be most abundant in animal cell ?

(1) t-RNA

(2) m-RNA

(3) mi-RNA

(4) r-RNA

Answer: 4


3. What is the criterion for DN A fragments movement on agarose gel during gel electrophoresis ?

(1) The smaller the fragment size, the farther it moves

(2) Positively charged fragments move to farther end

(3) Negatively charged fragments do not move

(4) The larger the fragment size, the farther it moves

Answer: 1


4. DNA replication in bacteria occurs___________

(1) Within nucleolus

(2) Prior to fission

(3) Just before transcription

(4) During S phase

Answer: 2


5. Taylor conducted the experiment to prove semiconservative mode of chromosome replication on_________

(1) Drosophila melanogaster

(2) E. coli

(3) Vinca rosea

(4) Vicia faba

Answer: 4


6. The equivalent of a structural gene is_________

(1) Operon

(2) Recon

(3) Muton

(4) Cistron

Answer: 4


7. Which of the following rRNAs acts as structural RNA as well as ribozyme in bacteria ?

(1) 23 S rRNA

(2) 5.8 S rRNA

(3) 5 S rRNA

(4) 18 S rRNA

Answer: 1


8. A non-proteinaceous enzyme is_______

(1) Ligase

(2) Deoxyribonuclease

(3) Lysozyme

(4) Ribozyme

Answer: 4


9. A molecule that can act as a genetic material must fulfill the traits given below,  except_____

(1) It should be unstable structurally and chemically

(2) It should provide the scope for slow changes that are required for evolution

(3) It should be able to express itself in the form of 'Mendelian characters'

(4) It should be able to generate its replica

Answer: 1


10. DNA-dependent RNA polymerase catalyzes transcription on one strand of the DNA which is called the___________

(1) Alpha strand

(2) Antistrand

(3) Template strand 

(4) Coding strand

Answer: 3


11. Antiparallel strands of a DNA molecule means that___________

(1) one strand turns anti-clockwise

(2 the phosphate groups of two DNA strands, at their ends, share the same position

(3) the phosphate groups at the start of two DNA strands are in opposite position (pole)

(4) one strand turns clockwise

Answer: 3


12. Differentiation of organs and tissues in a developing organism, is association with________

(1) Developmental mutations

(2) Differential expression of genes

(3) Lethal mutations

(4) Deletion of genes

Answer: 2


13. Molecular basis of organ differentiation depends on the modulation in transcription by________

(1) RNA polymerase 

(2) Ribosome

(3) Transcription factor 

(4) Anticodon

Answer: 3


14. The Okazaki fragments in DNA chain growth_______

(1) Result in transcription

(2) Polymerize in the 3'-to-5' direction and forms replication fork

(3) Prove semi-conservative nature of DNA replication

(4) Polymerize in the 5'-to-3' direction and explain 3'-to-5' DNA replication

Answer: 4


15. Cri-du-chat syndrome in humans is caused by the_________

(1) Fertilization of an XX egg by a normal Y-bearing sperm

(2) Loss of half of the short arm of chromosome 5

(3) Loss of half of the long arm of chromosome 5

(4) Trisomy of 21 stchromosome

Answer: 2


16. Polysome is formed by_______

(1) A ribosome with several subunits

(2) Ribosomes attached to each other in a linear arrangement

(3) Several ribosomes attached to a single mRNA

(4) Many ribosomes attached to a strand of endoplasmic reticulum

Answer: 3


17. Which one of the following pairs of nitrogenous bases of nucleic acids, is wrongly matched with the category mentioned against it ?

(1) Guanine, Adenine – Purines

(2) Adenine, Thymine – Purines

(3) Thymine, Uracil – Pyrimidines

(4) Uracil, Cytosine – Pyrimidines

Answer: 2


18. In the DNA molecule________

(1) the proportion of Adenine in relation to thymine varies with the organism

(2) there are two strands which run antiparallel one in 5' ------>3' direction and other in 3' -------> 5'

(3) the total amount of purine nucleotides and pyrimidine nucleotides is not always equal

(4) there are two strands which run parallel in the 5' ------->3' direction

Answer: 2


19. Which one of the following pairs of codons is correctly matched with their function or the signal for the particular amino acid ?

(1) AUG,ACG - Start/Methionine

(2) UUA, UCA –Leucine

(3) GUU, GCU –Alanine

(4) UAG, UGA – Stop

Answer: 4


20. Which of the following bond is not related to nucleic acid___________

(1) H-bond

(2) Ester bond

(3) Glycosidic bond

(4) Peptide bond

Answer: 4


21. Haploids are more suitable for mutation studies than the diploids. This is because________

(1) haploids are more abundant in nature than diploids

(2) All mutations, whether dominant or recessive are expressed in haploids

(3) Haploids are reproductively more stable than diploids

(4) Mutagens penetrate in haploids more effectively than in diploids

Answer: 2


22. What is not true for genetic code__________

(1) It is unambiguous

(2) A codon in mRNA is read in a non-contiguous fashion

(3) It is nearly universal

(4) It is degenerate

Answer: 2


23. Removal of introns and joining the exons in a defined order in a transcription unit is called________

(1) Capping

(2) Splicing

(3) Tailing

(4) Transformation

Answer: 2


24. Semiconservative replication of DNA was first demonstrated in________

(1) Salmonella typhimurium

(2) Drosophila melanogaster

(3) Escherichia coli

(4) Streptococcus pneumoniae

Answer: 3


25. Whose experiments cracked the DNA and discovered unequivocally that a genetic code is a "triplet"___________

(1) Beadle and tatum

(2) Nirenberg and Mathaei

(3) Hershey and Chase

(4) Morgan and Sturtevant

Answer: 2


26. Point mutation involves_________

(1) Deletion

(2) Insertion

(3) Change in single base pair

(4) Duplication

Answer: 3


27. Read the following four statements (A-D):

(A) In transcription, adenosine pairs with uracil.

(B) Regulation of lac operon by repressor is referred to as positive regulation.

(C) The human genome has approximately 50,000 genes.

(D) Haemophilia is a sex-linked recessive disease.

How many of the above statements are right?

(1) Four

(2) One

(3) Two

(4) Three

Answer: 3


28. Which one of the following is a wrong statement regarding mutations?

(1) UV and Gamma rays are mutagens

(2) Change in a single base pair of DNA does not cause mutation

(3) Deletion and insertion of base pairs cause frameshift mutations.

(4) Cancer cells commonly show chromosomal aberrations

Answer: 2


29. Which enzyme/s will be produced in a cell in which there is a nonsense mutation in the lac Y gene ?

(1) Lactose permease and transacetylase

(2) b-galactosidase

(3) Lactose permease

(4) Transacetylase

Answer: 2


30. DNA fragments generated by the restriction endonucleases in a chemical reaction can be separated by___________

(1) Restriction mapping

(2) Centrifugation

(3) Polymerase chain reaction

(4) Electrophoresis

Answer: 4

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